The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2024
Filed:
Jun. 22, 2018
Applicant:
Kymab Limited, Cambridge, GB;
Inventors:
Wei Wang, Cambridge, GB;
E-Chiang Lee, Cambridge, GB;
John Kenneth Blackwood, Cambridge, GB;
Roberto Magliozzi, Cambridge, GB;
Assignee:
KYMAB LIMITED, Cambridge, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/36 (2006.01); A61P 7/04 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C07K 16/36 (2013.01); A61P 7/04 (2018.01); C07K 16/40 (2013.01); C07K 2317/21 (2013.01); C07K 2317/31 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/64 (2013.01); C07K 2317/75 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
Bispecific antigen binding molecules (e.g., antibodies) that bind blood clotting factors, factor IXa (FIXa) and factor X (FX), and enhance the FIXa-catalysed activation of FX to FXa. Use of the bispecific antigen binding molecules to control bleeding, by replacing natural cofactor FVIIIa which is deficient in patients with haemophilia A.