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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11919965 B1

PDFFull Text
Date of Patent:
Mar. 05, 2024

Filed:

Dec. 04, 2020

Methods of treating multiple myeloma with bispecific anti-bcma x anti-cd3 antibodies

Applicant:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Inventors:

Israel Lowy, Dobbs Ferry, NY (US);

David Sternberg, New York, NY (US);

Manish Sharma, Scarsdale, NY (US);

Lieve Adriaens, Westfield, NJ (US);

Assignee:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorneys:

Schwabe, Williamson & Wyatt PC

Aparna Patankar

Primary Examiner:

Claire Kaufman

Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); C07K 16/2809 (2013.01); A61K 2039/507 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01);
Abstract

B-cell maturation antigen (BCMA) is expressed on malignant plasma cells. The present invention provides methods for treating multiple myeloma using bispecific antibodies (bsAbs) that bind to both BCMA and CD3 and activate T cells via the CD3 complex in the presence of BCMA-expressing tumor cells. In certain embodiments, the bispecific antigen-binding molecules of the present invention are capable of inhibiting the growth of tumors expressing BCMA.

Find Patent Forward Citations

Lowy, Israel. (2024). Methods of treating multiple myeloma with bispecific anti-bcma x anti-cd3 antibodies (U.S. Patent No. 11919965). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11919965

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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