The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2024
Filed:
Jul. 14, 2021
Amgen Inc., Thousand Oaks, CA (US);
Sue J. Sohn, Daly City, CA (US);
Marissa Mock, Newbury Park, CA (US);
Ian Nevin Foltz, Burnaby, CA;
Agnieszka Kielczewska, Vancouver, CA;
Kathy Manchulenko, Port Coquitlam, CA;
Yannick Bulliard, Thousand Oaks, CA (US);
Xiaoshan Min, Burlingame, CA (US);
AMGEN INC., Thousand Oaks, CA (US);
Abstract
Provided herein are TIGIT binding proteins, CD112R binding proteins, and combinations thereof. Also provided are compositions comprising TIGIT binding proteins and CD112R binding proteins, optionally further comprising PD-1 binding proteins. Related conjugates, fusion proteins, nucleic acids, vectors, host cells and kits are additionally provided. Further provided are pharmaceutical compositions comprising a TIGIT binding protein, CD112R binding protein, or a combination thereof, optionally, further comprising a PD-1 antigen binding protein, or a conjugate, fusion protein, nucleic acid, vector, or host cell, and a pharmaceutically acceptable carrier, diluent, or excipient, and methods of treating subjects in need thereof.