The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2024
Filed:
May. 23, 2018
Applicant:
Université DE Genéve, Geneva, CH;
Inventor:
Karim Brandt, Geneva, CH;
Assignee:
Université de Genève, Geneva, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/74 (2006.01); C07K 7/06 (2006.01); G01N 33/564 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70539 (2013.01); C07K 7/06 (2013.01); G01N 33/564 (2013.01); A61K 38/00 (2013.01); G01N 2800/24 (2013.01);
Abstract
The invention provides an isolated peptide containing a motif that binds antiphospholipid antibodies (aPLA) and that is recognized by CD4+ T cells that are able to induce production of antiphospholipid antibodies (aPLA). The present invention further provides methods for detection of aPLA and CD4+ T cells able to induce production of aPLA. The present invention also provides methods for treating the antiphospholipid syndrome (APS).