The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2024

Filed:

Oct. 12, 2021
Applicant:

Kumiai Chemical Industry Co., Ltd., Tokyo, JP;

Inventors:

Takashi Kubo, Sapporo, JP;

Masayuki Machida, Sapporo, JP;

Tomonori Fujioka, Tokyo, JP;

Shigenari Yamaguchi, Tokyo, JP;

Kiyoshi Kawai, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/37 (2006.01); C07K 7/64 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 15/70 (2006.01); C12N 15/75 (2006.01); C12N 15/77 (2006.01); C12N 15/78 (2006.01); C12N 15/81 (2006.01); C12P 21/02 (2006.01); C12N 1/14 (2006.01);
U.S. Cl.
CPC ...
C07K 14/37 (2013.01); C07K 7/64 (2013.01); C12N 9/0077 (2013.01); C12N 9/10 (2013.01); C12N 9/1007 (2013.01); C12N 15/70 (2013.01); C12N 15/75 (2013.01); C12N 15/77 (2013.01); C12N 15/78 (2013.01); C12N 15/81 (2013.01); C12P 21/02 (2013.01); C12N 1/14 (2013.01);
Abstract

An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.


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