The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2024
Filed:
Dec. 20, 2018
Applicant:
Fresenius Kabi Deutschland Gmbh, Bad Homburg, DE;
Inventors:
Assignee:
FRESENIUS KABI DEUTSCHLAND GMBH, Bad Homburg, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/18 (2006.01); A61K 39/395 (2006.01); B01D 15/38 (2006.01); B01J 20/04 (2006.01); C07K 1/20 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
C07K 1/18 (2013.01); A61K 39/39591 (2013.01); B01D 15/3847 (2013.01); B01J 20/048 (2013.01); C07K 1/20 (2013.01); C07K 16/241 (2013.01);
Abstract
The present invention relates to a method for purifying adalimumab or a biosimilar thereof from a sample comprising adalimumab or a biosimilar thereof and impurities, through the use of hydroxyapatite resin in a Bind/Elute (B/E) mode under conditions such that the adalimumab or a biosimilar thereof binds to the resin and at least a portion of the impurities remain unbound. The invention is also concerned with a pharmaceutical compositions=of the purified adalimumab or a biosimilar thereof, and adalimumab or a biosimilar thereof obtainable by the process of the invention.