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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11919924 B1

PDFFull Text
Date of Patent:
Mar. 05, 2024

Filed:

Dec. 20, 2018

Methods of purifying and producing an adalimumab antibody

Applicant:

Fresenius Kabi Deutschland Gmbh, Bad Homburg, DE;

Inventors:

Harry-James Sutter, Vevey, CH;

Matteo Costioli, Lausanne, CH;

Hervé Broly, Chatel-St Denis, CH;

Assignee:

FRESENIUS KABI DEUTSCHLAND GMBH, Bad Homburg, DE;

Attorney:

Fox Rothschild LLP

Primary Examiner:

Michelle S Horning

Int. Cl.
CPC ...
C07K 1/18 (2006.01); A61K 39/395 (2006.01); B01D 15/38 (2006.01); B01J 20/04 (2006.01); C07K 1/20 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
C07K 1/18 (2013.01); A61K 39/39591 (2013.01); B01D 15/3847 (2013.01); B01J 20/048 (2013.01); C07K 1/20 (2013.01); C07K 16/241 (2013.01);
Abstract

The present invention relates to a method for purifying adalimumab or a biosimilar thereof from a sample comprising adalimumab or a biosimilar thereof and impurities, through the use of hydroxyapatite resin in a Bind/Elute (B/E) mode under conditions such that the adalimumab or a biosimilar thereof binds to the resin and at least a portion of the impurities remain unbound. The invention is also concerned with a pharmaceutical compositions=of the purified adalimumab or a biosimilar thereof, and adalimumab or a biosimilar thereof obtainable by the process of the invention.

Find Patent Forward Citations

Sutter, Harry-James. (2024). Methods of purifying and producing an adalimumab antibody (U.S. Patent No. 11919924). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11919924

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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