The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2024

Filed:

May. 18, 2022
Applicant:

Biomarin Pharmaceutical Inc., Novato, CA (US);

Inventor:

Debra Lounsbury, San Francisco, CA (US);

Assignee:

BIOMARIN PHARMACEUTICAL INC., Novato, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/88 (2006.01); A61K 38/51 (2006.01); A61P 3/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/51 (2013.01); A61P 3/00 (2018.01); C12Y 403/01024 (2013.01);
Abstract

Phenylalanine ammonia-lyase (PAL) variants with a greater phenylalanine-converting activity and/or a reduced immunogenicity as compared to a wild-type PAL for therapeutic uses, including the treatment of adolescent subjects having PKU.


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