The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2024

Filed:

Nov. 19, 2018
Applicant:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Jenny P.-Y. Ting, Chapel Hill, NC (US);

Willie June Brickey, Durham, NC (US);

Hao Guo, Hillsborough, NC (US);

Cathryn Julia Robbins, Redwood City, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2019.01); A61K 9/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61P 35/00 (2018.01);
Abstract

Provided herein are methods of mitigating and/or preventing side effects from chemotherapy and/or radiotherapy in a subject by administering a therapeutically effective amount of a toll-like receptor 2/6 (TLR 2/6) ligand, including fibroblast-stimulating lipopeptide 1 (FSL-1). Methods of treating and/or preventing gastrointestinal disorders are also disclosed. Additionally, methods of increasing granulocyte colony-stimulating factor (G-CSF) production in a subject undergoing a medical treatment, including administering FSL-1 compositions, are provided.


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