The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2024

Filed:

Mar. 09, 2018
Applicant:

Ajou University Industry-academic Cooperation Foundation, Suwon-si, KR;

Inventors:

Hyun-Chul Yoon, Seoul, KR;

Jae-Ho Kim, Suwon-si, KR;

Yong-Duk Han, Seongnam-si, KR;

Hyeong-Jin Chun, Suwon-si, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/55 (2014.01); G02B 5/126 (2006.01); G02B 5/128 (2006.01); G02B 5/12 (2006.01); C12Q 1/6825 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6825 (2013.01); G01N 21/55 (2013.01); G02B 5/126 (2013.01); G02B 5/128 (2013.01); G01N 2021/551 (2013.01); G01N 2201/0636 (2013.01); G02B 5/12 (2013.01);
Abstract

An optical gene biosensor is disclosed. The optical gene biosensor includes a substrate; a molecular beacon anchored to the substrate, wherein the molecular beacon includes an oligonucleotide specifically binding to a target nucleic acid molecule and a first compound bound to a first terminal of the oligonucleotide; an optical marker specifically binding to the first compound, wherein the optical marker is configured to retro-reflect irradiated light; a light source for irradiating the optical marker with light; and a light-receiver for receiving light retro-reflected from the optical marker. The optical gene biosensor may perform accurate quantitative analysis of a target nucleic acid molecule using both non-spectral and spectral light sources.


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