The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2024
Filed:
Jul. 10, 2020
Applicant:
Genome Research Limited, Hinxton, GB;
Inventors:
Pengtao Liu, Hinxton, GB;
David Ryan, Hinxton, GB;
Xuefei Gao, Hinxton, GB;
Wei Wang, Hinxton, GB;
Jian Yang, Hinxton, GB;
Assignee:
GENOME RESEARCH LIMITED, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01); C12N 5/073 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0018 (2013.01); A01K 67/0275 (2013.01); C12N 5/0605 (2013.01); C12N 5/0606 (2013.01); C12N 5/0696 (2013.01); A01K 2217/05 (2013.01); C12N 2500/38 (2013.01); C12N 2500/99 (2013.01); C12N 2501/105 (2013.01); C12N 2501/16 (2013.01); C12N 2501/235 (2013.01); C12N 2501/33 (2013.01); C12N 2501/415 (2013.01); C12N 2501/602 (2013.01); C12N 2501/603 (2013.01); C12N 2501/604 (2013.01); C12N 2501/605 (2013.01); C12N 2501/606 (2013.01); C12N 2501/608 (2013.01); C12N 2501/727 (2013.01); C12N 2501/999 (2013.01); C12N 2506/45 (2013.01);
Abstract
A culture medium is provided which is capable of establishing expanded potential stem cell (EPSC) lines which resemble naïve or ground state ES cells, but are also able to differentiate into placenta trophoblasts and the embryo proper. Methods are provided using the medium for the in vitro conversion and maintenance of cells, including pluripotent cells into EPSCs.