The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2024

Filed:

Apr. 17, 2018
Applicant:

University of Maryland, College Park, College Park, MD (US);

Inventors:

Chi-Hun Park, Laurel, MD (US);

Bhanu Prakash V. L. Telugu, Columbia, MD (US);

Assignee:

UNIVERSITY OF MARYLAND, COLLEGE PARK, College Park, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/877 (2010.01); A01K 67/027 (2006.01); C12N 5/073 (2010.01);
U.S. Cl.
CPC ...
C12N 15/877 (2013.01); A01K 67/027 (2013.01); C12N 5/0605 (2013.01); C12N 2510/00 (2013.01); C12N 2830/008 (2013.01);
Abstract

The invention provides a composition comprising an extraembryonic endodermal (XEN) call and/or an embryonic fibroblast (EF) cell. The invention also provides a method of establishing a XEN cell line or a primary embryonic fibroblast (EF) cell line in vitro, the method comprising culturing a zygote or parthenote from a mammal for a time sufficient to produce one or more blastocysts; and culturing the one or more blastocysts on feeder cells in culture medium for a time sufficient to produce one or a plurality of XEN cells and/or one or a plurality of EF cells.


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