The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2024

Filed:

Jul. 30, 2021
Applicants:

The Government of the United States of America As Represented BY the Secretary of the Department of Health and Human Services, Rockville, MD (US);

Sabin Vaccine Institute, Washington, DC (US);

Inventors:

Nancy J. Sullivan, Kensington, MD (US);

Gary J. Nabel, Washington, DC (US);

Clement Asiedu, Olney, MD (US);

Cheng Cheng, Rockville, MD (US);

Alfredo Nicosia, Rome, IT;

Riccardo Cortese, Rome, IT;

Virginia Ammendola, Naples, IT;

Stefano Colloca, Rome, IT;

Assignee:

SABIN VACCINE INSTITUTE, Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 15/861 (2006.01); C07K 14/08 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01); C12N 15/863 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 39/12 (2013.01); C07K 14/005 (2013.01); C07K 14/08 (2013.01); C12N 15/861 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/545 (2013.01); C12N 7/00 (2013.01); C12N 15/8636 (2013.01); C12N 2710/10341 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/24111 (2013.01); C12N 2710/24141 (2013.01); C12N 2760/14111 (2013.01); C12N 2760/14134 (2013.01);
Abstract

This invention provides vaccines for inducing an immune response and protection against filovirus infection for use as a preventative vaccine in humans. In particular, the invention provides chimpanzee adenoviral vectors expressing filovirus proteins from different strains of Ebolavirus (EBOV) or Marburg virus (MARV).


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