The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2024

Filed:

Jul. 19, 2019
Applicants:

Sunnybrook Research Institute, Toronto, CA;

The Governing Council of the University of Toronto, Toronto, CA;

Inventors:

Richard Cheng, Toronto, CA;

Gertraud Eylert, Vienna, AT;

Sijin He, Beijing, CN;

Jean-Michel Gariépy, Toronto, CA;

Navid Hakimi, Toronto, CA;

Marc G. Jeschke, Toronto, CA;

Axel Guenther, Toronto, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B29C 67/00 (2017.01); A61F 2/10 (2006.01); A61L 27/20 (2006.01); A61L 27/22 (2006.01); A61L 27/24 (2006.01); A61L 27/26 (2006.01); A61L 27/54 (2006.01); A61M 35/00 (2006.01); B29C 64/209 (2017.01); B29C 64/25 (2017.01); B29C 64/264 (2017.01); B29C 64/393 (2017.01); B33Y 30/00 (2015.01); B33Y 50/02 (2015.01); C12M 1/32 (2006.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
A61M 35/003 (2013.01); A61F 2/105 (2013.01); A61L 27/20 (2013.01); A61L 27/225 (2013.01); A61L 27/24 (2013.01); A61L 27/26 (2013.01); A61L 27/54 (2013.01); B29C 64/209 (2017.08); B29C 64/25 (2017.08); B29C 64/264 (2017.08); B29C 64/393 (2017.08); B33Y 30/00 (2014.12); B33Y 50/02 (2014.12); C12M 33/06 (2013.01); A61F 2240/002 (2013.01); A61L 2300/412 (2013.01); A61L 2300/414 (2013.01); A61L 2430/34 (2013.01); A61L 2430/40 (2013.01); A61M 2210/04 (2013.01); B29K 2995/0056 (2013.01); B29L 2031/753 (2013.01);
Abstract

Disclosed herein is an instrument that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface such as a patient having burn injuries. In handheld embodiments of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printer head and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. A soft deformable roller mitigates further damage to the injured area of skin as it rolls over it and a gimbal mechanism to which the printer head is attached is in contact with the injured tissue but is configured so that the printer head while in contact with tissue, does not exert undue pressure on the would area.


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