The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2024

Filed:

May. 03, 2013
Applicants:

Indiana University Research & Technology Corporation, Indianapolis, IN (US);

United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Robert Bacallao, Indianapolis, IN (US);

Simon Atkinson, Carmel, IN (US);

George Rhodes, Fishers, IN (US);

Peter Corridon, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/00 (2006.01); A61K 48/00 (2006.01); A61K 9/00 (2006.01); A61K 38/44 (2006.01); A61K 38/45 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0075 (2013.01); A61K 9/0019 (2013.01); A61K 38/443 (2013.01); A61K 38/45 (2013.01); A61K 48/0058 (2013.01); C12N 7/00 (2013.01); C12Y 101/01042 (2013.01); C12Y 208/02 (2013.01); C12N 2710/10041 (2013.01);
Abstract

The present invention provides methods and materials useful delivering liquids, including liquids comprising nucleic acid molecules into cells. In particular, the present invention provides methods for delivering saline solution, exogenous compositions, and isolated vectors to kidney cells, using the renal vein as a guide and under hydrodynamic pressure. The delivery methods and materials herein are useful to research, prognose, ameliorate symptoms of kidney injury, and treat kidney pathologies.


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