The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2024

Filed:

Jul. 25, 2018
Applicant:

PK Med Sas, Paris, FR;

Inventors:

Philippe Pouletty, Paris, FR;

Frédérique Guillamot, Gerzat, FR;

Assignee:

PK MED, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); B29C 48/00 (2019.01); A61K 31/485 (2006.01); A61K 38/47 (2006.01); A61L 17/12 (2006.01); A61L 24/00 (2006.01); A61L 24/04 (2006.01); A61L 27/18 (2006.01); A61L 27/54 (2006.01); A61L 31/06 (2006.01); A61L 31/16 (2006.01); C07K 16/24 (2006.01); B29K 67/00 (2006.01); B29K 105/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 31/485 (2013.01); A61K 38/47 (2013.01); A61L 17/12 (2013.01); A61L 24/0015 (2013.01); A61L 24/046 (2013.01); A61L 27/18 (2013.01); A61L 27/54 (2013.01); A61L 31/06 (2013.01); A61L 31/16 (2013.01); B29C 48/022 (2019.02); C07K 16/241 (2013.01); A61L 2300/216 (2013.01); A61L 2300/254 (2013.01); B29K 2067/043 (2013.01); B29K 2067/046 (2013.01); B29K 2105/0035 (2013.01); B29K 2105/0085 (2013.01);
Abstract

The present invention relates to process for preparing a drug delivery composition comprising the steps of a) preparing a masterbatch comprising a drug and a first polymer by (i) extruding the first polymer, wherein said first polymer has a melting temperature below 140° C.; and (ii) introducing the drug during extrusion of the first polymer, with a drug content between 0.1% and 90%, based on the total weight of the masterbatch; and b) introducing the masterbatch in a polymer-based matrix during production of the drug delivery composition, wherein step a) is performed at a temperature at which the first polymer is in a partially or totally molten state, and step b) is performed at a temperature at which both the first polymer and at least a polymer of the polymer-based matrix are in a partially or totally molten state.


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