The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2024

Filed:

Nov. 17, 2020
Applicant:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Inventors:

Lisa Purcell, Garnerville, NY (US);

Alexander O. Mujica, Elmsford, NY (US);

Yajun Tang, White Plains, NY (US);

Assignee:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C12N 15/09 (2006.01); C12N 15/63 (2006.01); C12N 9/64 (2006.01); C12N 5/0735 (2010.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0275 (2013.01); A01K 67/0278 (2013.01); C07K 14/47 (2013.01); C12N 5/0606 (2013.01); C12N 9/6424 (2013.01); C12N 15/63 (2013.01); C12N 15/86 (2013.01); A01K 2207/15 (2013.01); A01K 2217/072 (2013.01); A01K 2227/10 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0337 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01); C12N 15/09 (2013.01); C12N 2710/10332 (2013.01);
Abstract

Genetically modified rodents such as mice and rats, and methods and compositions for making and using the same, are provided. The rodents comprise a humanization of at least one endogenous rodent Tmprss gene, such as an endogenous rodent Tmprss2, Tmprss4, or Tmprss11d gene.


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