The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2024

Filed:

Jul. 27, 2017
Applicant:

The Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

Chengcheng Zhang, Dallas, TX (US);

Zhiqiang An, Houston, TX (US);

Ningyan Zhang, Houston, TX (US);

Mi Deng, Plano, TX (US);

Jaehyup Kim, Houston, TX (US);

Xun Gui, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 15/14 (2006.01); G01N 21/64 (2006.01); G01N 33/50 (2006.01); G01N 33/49 (2006.01); G01N 15/00 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57426 (2013.01); G01N 15/14 (2013.01); G01N 21/6428 (2013.01); G01N 21/6456 (2013.01); G01N 33/4915 (2013.01); G01N 33/5023 (2013.01); G01N 33/57492 (2013.01); G01N 2015/0065 (2013.01); G01N 2015/1006 (2013.01); G01N 2021/6439 (2013.01);
Abstract

Provided herein are methods and compositions for the identification of modulators of ApoE-induced LILRB activation. Also provided herein are methods of treating cancer comprising the administration of an inhibitor of ApoE-induced LILRB activation. Also provided are methods of treating autoimmune disease or inhibiting the onset of transplant rejection or treating an inflammatory disorder comprising administering an agonist of ApoE-induced LILRB activation to a subject.


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