The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2024

Filed:

Apr. 21, 2021
Applicant:

X Development Llc, Mountain View, CA (US);

Inventors:

Ivan Grubisic, Oakland, CA (US);

Ray Nagatani, San Francisco, CA (US);

Assignee:

X Development LLC, Mountain View, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G16B 5/20 (2019.01); C12N 15/115 (2010.01); C40B 30/04 (2006.01); G16C 20/20 (2019.01); G16C 20/50 (2019.01); G16C 20/70 (2019.01);
U.S. Cl.
CPC ...
G01N 33/574 (2013.01); C12N 15/115 (2013.01); C40B 30/04 (2013.01); G16B 5/20 (2019.02); G16C 20/20 (2019.02); G16C 20/50 (2019.02); G16C 20/70 (2019.02); C12N 2310/16 (2013.01); C12N 2320/10 (2013.01); G01N 2500/10 (2013.01);
Abstract

Methods described herein include receiving data from flowing a plurality of aptamers over a sample of tumor cells randomly affixed to a surface of a microfluidic device. The tumor cells may include one or more unknown tumor subtypes of cells. The plurality of aptamers may include a plurality of aptamer families. Each aptamer family of the plurality of aptamer families may be determined to bind to at least one possible subtype of the tumor cells. The data may include a measure of binding affinity of each aptamer family to the tumor cells. The method may include analyzing the measure of the binding affinity of each aptamer family to the tumor cells. The analyzing may include classifying the binding affinity. The method may also include determining one or more aptamer families that characterize the one or more unknown tumor subtypes of cells based on the classifying.


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