The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2024
Filed:
Mar. 05, 2021
Life Technologies Corporation, Carlsbad, CA (US);
Swati Goyal, San Mateo, CA (US);
Achim Karger, Foster City, CA (US);
Peter Ma, Cupertino, CA (US);
S. Jeffrey Rosner, Palo Alto, CA (US);
Ian Walton, Redwood City, CA (US);
Jonathan Wang, Mountain View, CA (US);
Michael Wenz, Redwood City, CA (US);
LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);
Abstract
According to various embodiments described herein, a microfluidics-chip based purification device and system for Sanger-sequencing reactions is provided. The device and system allow for the introduction into a sequencing system of a cartridge containing purification technologies specific to the sequencing contaminants or sequencing method where the simplified purification solution of a cartridge allows automation of the sample purification process, reduced consumption of purification reagents, and consistency in sampling by reducing the sampling errors and artifacts. These various embodiments therefore solve the need for a microfluidics-chip-based, Sanger-sequencing reaction purification system for CE devices. The microfluidic chips described can be used as a PCR chip by reorganizing the on-chip reagents, reaction wells and work flow steps.