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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11905528 B1

PDFFull Text
Date of Patent:
Feb. 20, 2024

Filed:

Oct. 12, 2018

Compound chimeric antigen receptor (ccar) targeting multiple antigens, compositions and methods of use thereof

Applicant:

Icell Gene Therapeutics, Llc, Stony Brook, NY (US);

Inventors:

Yupo Ma, Stony Brook, NY (US);

Kevin Pinz, Stony Brook, NY (US);

Xun Jiang, Stony Brook, NY (US);

Masayuki Wada, Stony Brook, NY (US);

Kevin Chen, Stony Brook, NY (US);

Assignee:

ICell Gene Therapeutics Inc., Stony Brook, NY (US);

Attorney:

Hoffmann & Baron, LLP

Primary Examiner:

Peter J Reddig

Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61P 35/00 (2006.01); A61K 35/17 (2015.01); C07K 14/435 (2006.01); C07K 14/54 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 14/73 (2006.01); C07K 14/715 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 14/435 (2013.01); C07K 14/54 (2013.01); C07K 14/5443 (2013.01); C07K 14/705 (2013.01); C07K 14/7051 (2013.01); C07K 14/70503 (2013.01); C07K 14/70514 (2013.01); C07K 14/70575 (2013.01); C07K 14/70589 (2013.01); C07K 14/7155 (2013.01); C12N 5/0646 (2013.01); C12N 9/1081 (2013.01); C07K 2319/03 (2013.01); C12N 2510/00 (2013.01);
Abstract

In one embodiment, the present disclosure provides an engineered cell having a first chimeric antigen receptor polypeptide including a first antigen recognition domain, a first signal peptide, a first hinge region, a first transmembrane domain, a first costimulatory domain, and a first signaling domain; and a second chimeric antigen receptor polypeptide including a second antigen recognition domain, a second signal peptide, a second hinge region, a second transmembrane domain, a second co-stimulatory domain, and a second signaling domain; wherein the first antigen recognition domain is different than the second antigen recognition domain.

Find Patent Forward Citations

Ma, Yupo. (2024). Compound chimeric antigen receptor (ccar) targeting multiple antigens, compositions and methods of use thereof (U.S. Patent No. 11905528). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11905528

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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