The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2024

Filed:

Oct. 11, 2018
Applicant:

Mbp Titan Llc, South San Francisco, CA (US);

Inventors:

Xuezhi Li, Hayward, CA (US);

James Kealey, Sebastopol, CA (US);

Kevin Lee Dietzel, Pacifica, CA (US);

Assignee:

MBP TITAN, LLC, South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 1/20 (2006.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C12N 1/20 (2013.01); C12N 9/22 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract

Methods of genetically modifying microorganisms using advanced genome editing are disclosed. Methods of modifying the genome of these microorganisms for point mutations, deletions, and DNA insertions are also disclosed. Further, inhibiting expression of genes without manipulating the genome of the microorganism is disclosed. In some cases, the microorganism can be a methylotroph, e.g., a methanotroph.


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