The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2024
Filed:
Jun. 29, 2018
Applicant:
Fred Hutchinson Cancer Center, Seattle, WA (US);
Inventors:
Harlan S. Robins, Seattle, WA (US);
Edus H. Warren, Bainbridge Island, WA (US);
Christopher Scott Carlson, Kirland, WA (US);
Assignee:
Fred Hutchinson Cancer Center, Seattle, WA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); G16B 40/00 (2019.01); C12Q 1/6883 (2018.01); C12Q 1/6874 (2018.01); C12Q 1/6869 (2018.01); C12Q 1/6881 (2018.01);
U.S. Cl.
CPC ...
C12N 15/1065 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6874 (2013.01); C12Q 1/6881 (2013.01); C12Q 1/6883 (2013.01); G16B 40/00 (2019.02); C12Q 2600/16 (2013.01);
Abstract
A method of measuring immunocompetence is described. This method provides a means for assessing the effects of diseases or conditions that compromise the immune system and of therapies aimed to reconstitute it. This method is based on quantifying T-cell diversity by calculating the number of diverse T-cell receptor (TCR) beta chain variable regions from blood cells.