The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2024

Filed:

Aug. 22, 2022
Applicant:

Southern Research Institute, Birmingham, AL (US);

Inventors:

Mark J. Suto, Homewood, AL (US);

Bini Mathew, Hoover, AL (US);

Rita Cowell, Hoover, AL (US);

Corinne E. Augelli-Szafran, Homewood, AL (US);

Assignee:

Southern Research Institute, Birmingham, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/48 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
C07D 263/48 (2013.01); C07D 413/04 (2013.01);
Abstract

The present disclosure is concerned with 2-aminoaryl-5-aryloxazole compounds that are capable of activating NF-κB signaling. The present disclosure is also concerned with methods of using these compounds for the treatment of neurological disorders such as, for example, amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, traumatic brain injury, vascular dementia, Huntington's disease, mental retardation, and attention deficit and hyperactivity disorder (ADHD), and neuromuscular disorders such as, for example, Duchenne muscular dystrophy (DMD). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


Find Patent Forward Citations

Loading…