The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2024
Filed:
Feb. 08, 2019
Applicant:
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Inventors:
Joel Schneider, Frederick, MD (US);
Poulami Majumder, Frederick, MD (US);
Chuong Hoang, Bethesda, MD (US);
Anand Singh, Bethesda, MD (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 31/7105 (2006.01); A61K 47/64 (2017.01); A61K 47/69 (2017.01); A61K 45/06 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 9/5169 (2013.01); A61K 31/7105 (2013.01); A61K 47/6455 (2017.08); A61K 47/6929 (2017.08); A61K 45/06 (2013.01); B82Y 5/00 (2013.01);
Abstract
This disclosure provides novel peptide hydrogels containing encapsulated nanoparticles comprising nucleic acid molecules (such as miRNA) that can undergo multiple gel-to-solution (gel-sol) and solution-to-gel (sol-gel) phase transitions, and their use, such as for controlled delivery of nucleic acid molecules to a subject.