The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2024

Filed:

Apr. 18, 2019
Applicant:

Pds Biotechnology Corporation, North Brunswick, NJ (US);

Inventors:

Frank Bedu-Addo, Bethel, CT (US);

Eric Jacobson, Cincinnati, OH (US);

Kenya Johnson, Mason, OH (US);

Assignee:

PDS BIOTECHNOLOGY CORPORATION, Berkeley Heights, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 39/12 (2006.01); A61K 39/02 (2006.01); A61K 39/145 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 39/0002 (2013.01); A61K 39/0005 (2013.01); A61K 39/02 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/70 (2013.01); C12N 2760/16034 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16234 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present disclosure provides vaccine compositions comprising at least one adjuvant and at least one antigen, wherein the adjuvant is a cationic lipid. The disclosure also provides methods of treating a disease in a mammal, methods of preventing a disease in a mammal, and methods of effecting antigen cross presentation to induce a humoral immune response and a cellular immune response in a mammal utilizing the vaccine compositions. Cross presentation of various antigens can be achieved by formulating the specific antigens with cationic lipids possessing adjuvant properties.


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