The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2024
Filed:
Oct. 01, 2020
Applicant:
Sanofi, Paris, FR;
Inventors:
Gary J. Nabel, Bridgewater, NJ (US);
Chih-Jen Wei, Bridgewater, NJ (US);
Kurt Swanson, Bridgewater, NJ (US);
Assignee:
SANOFI, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61P 37/04 (2006.01); A61P 31/04 (2006.01); A61P 31/16 (2006.01); C07K 14/005 (2006.01); C07K 14/195 (2006.01);
U.S. Cl.
CPC ...
A61K 39/105 (2013.01); A61K 39/0225 (2013.01); A61P 31/04 (2018.01); A61P 31/16 (2018.01); A61P 37/04 (2018.01); C07K 14/005 (2013.01); C07K 14/195 (2013.01); C07K 2319/00 (2013.01); C12N 2710/16222 (2013.01); C12N 2710/16234 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/18522 (2013.01); C12N 2760/18534 (2013.01);
Abstract
Ferritin proteins comprising a mutation replacing a surface-exposed amino acid with a cysteine, an N- or C-terminal linker comprising a cysteine, and/or one or more immune-stimulatory moieties linked to the ferritin protein via a surface-exposed amino acid are disclosed. The ferritin proteins can further comprise a non-ferritin polypeptide and be antigenic, e.g., for use in eliciting antibodies against the non-ferritin polypeptide.