The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2024

Filed:

May. 26, 2021
Applicants:

Northwestern University, Evanston, IL (US);

Case Western Reserve University, Cleveland, OH (US);

The Regents of the University of Colorado, Denver, CO (US);

Inventors:

Kurt Q. Lu, Chicago, IL (US);

Livia A. Veress, Denver, CO (US);

Kevin D. Cooper, Moreland Hills, OH (US);

Amisha Wallia, Chicago, IL (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/593 (2006.01); A61K 45/06 (2006.01); A61P 31/14 (2006.01); A61P 11/00 (2006.01); A61K 31/585 (2006.01);
U.S. Cl.
CPC ...
A61K 31/593 (2013.01); A61K 31/585 (2013.01); A61K 45/06 (2013.01); A61P 11/00 (2018.01); A61P 31/14 (2018.01);
Abstract

Disclosed herein are methods and compositions useful in reducing inflammation, reducing inflammatory exudates, enhancing epithelial tissue generation or regeneration, and/or reducing mean pulmonary artery pressure in the lungs of a subject in need thereof. In particular, the compositions comprise vitamin D, an analog, or metabolite thereof, and the methods include administering the composition to a subject in need thereof. In some embodiments, the subject is suffering from an infection, such as a viral infection, which affects the lungs. In some embodiments, the viral infection comprises SARS-CoV-2.


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