The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2024

Filed:

Sep. 03, 2021
Applicant:

University of Georgia Research Foundation, Inc., Athens, GA (US);

Inventors:

Ralph A. Tripp, Watkinsville, GA (US);

Jackelyn Murray, Monroe, GA (US);

Robert Jeff Hogan, Watkinsville, GA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/195 (2006.01); A61K 31/63 (2006.01); A61P 31/12 (2006.01); A61P 31/14 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/195 (2013.01); A61P 31/14 (2018.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01);
Abstract

Compositions and methods of treating a subject for a coronavirus infection are provided. The methods typically include administering the subject an effective amount of probenecid, a metabolite or analog thereof, or a pharmaceutically acceptable salt thereof. The methods can by therapeutic and/or prophylactic. The amount of probenecid or a pharmaceutically acceptable salt thereof can be effective to, for example, reduce viral replication, reduce one or more symptoms of disease, disorder, or illness associated with virus, or a combination thereof. In preferred embodiments, the virus is a Severe acute respiratory syndrome-related coronavirus such as SARS-CoV-2 or SARS-CoV, a Middle East respiratory syndrome-related coronavirus such as MERS-CoV, or a coronavirus that causes the common cold.


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