The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Jun. 19, 2020
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Virginia Wood Cornish, New York, NY (US);

Nili Ostrov, Brookline, MA (US);

Miguel Jimenez, Winthrop, MA (US);

Sonja Billerbeck, Groningen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/566 (2006.01); C12Q 1/02 (2006.01); G01N 33/74 (2006.01); G01N 33/50 (2006.01); C12Q 1/00 (2006.01); C12Q 1/06 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/566 (2013.01); C12Q 1/005 (2013.01); C12Q 1/02 (2013.01); C12Q 1/025 (2013.01); C12Q 1/06 (2013.01); G01N 33/5023 (2013.01); G01N 33/5038 (2013.01); G01N 33/569 (2013.01); G01N 33/5695 (2013.01); G01N 33/56911 (2013.01); G01N 33/56916 (2013.01); G01N 33/56961 (2013.01); G01N 33/74 (2013.01); G01N 2333/726 (2013.01);
Abstract

The present invention provides sensor cells comprising a receptor that binds to an analyte indicative of the presence of an agent, where binding of the analyte to the receptor triggers a detection event that is indicative of the presence of the agent. In certain embodiments, the detection event is appearance of a reporter detectable by the naked eye. The present invention also provides uses of such sensor cells for detecting the presence of an agent in a sample.


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