The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Nov. 21, 2019
Applicant:

Arex Life Sciences, Llc, Watertown, MA (US);

Inventor:

Barb A. Cohen, Watertown, MA (US);

Assignee:

AREX LIFE SCIENCES, LLC, Watertown, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/569 (2006.01); C12N 5/076 (2010.01); A01N 1/02 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5091 (2013.01); A01N 1/0284 (2013.01); C12N 5/061 (2013.01); G01N 33/56966 (2013.01);
Abstract

A method for adjusting the maturation state of mammalian sperm for use in assisted reproductive technologies (ART) is disclosed. A mammalian ejaculate is provided and incubated under controlled conditions. Aliquots of the ejaculate are assayed during incubation period at intervals to determine maturation state and changes in the maturation state by observing the percent positive cells in the aliquot. The assays are repeated with successive aliquots at intervals during incubation to observe real time changes in the maturation state. The ejaculate remaining is processed for the desired ART after the percentage of positive cells in the latest aliquot being assayed begins to decline.


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