The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Apr. 02, 2020
Applicant:

Alio, Inc., Broomfield, CO (US);

Inventors:

Forrest Miller, Philadelphia, PA (US);

Samit Kumar Gupta, Menlo Park, CA (US);

David John Kuraguntla, Bel Air, MD (US);

Elsa Swanson, Cherry Hill, NJ (US);

Assignee:

Alio, Inc., San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 21/51 (2006.01); G01N 21/84 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 21/8483 (2013.01); G01N 21/51 (2013.01); G01N 33/5094 (2013.01); G01N 2333/4737 (2013.01); G01N 2333/914 (2013.01); G01N 2800/26 (2013.01);
Abstract

A system, device and method for measuring markers for a periprosthetic joint infection in a sample of synovial fluid. A sensor reader device includes a vial receptacle for receiving a vial containing synovial fluid. A light source illuminates the vial and an optical sensor detects light scattered and/or absorbed by white blood cells in the fluid sample. An electrical signal corresponding to the intensity of the light received at the optical sensor is detected. A white blood cell concentration is determined from the electrical signal value. The sensor reader device also includes one or more immunoassay strip receptacles. Immunoassay strips for other marker are inserted into the receptacles. Immunoassay optical sensors detect light generated by the immunoassay reaction on the immunoassay strip to determine the concentration of the marker. In example implementations, the device includes an immunoassay strip reader for leukocyte esterase and c-reactive protein.


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