The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Oct. 08, 2020
The General Hospital Corporation, Boston, MA (US);
Daniel A. Haber, Chestnut Hill, MA (US);
Ravi Kapur, Sharon, MA (US);
Mehmet Toner, Charlestown, MA (US);
Shyamala Maheswaran, Lexington, MA (US);
Xin Hong, Medford, MA (US);
David Tomoaki Miyamoto, Wellesley, MA (US);
Tanya Todorova, Malden, MA (US);
Sarah Javaid, Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
This disclosure relates to new assay methods for analysis of circulating tumor cells (CTCs) in blood samples for detection, e.g., early detection, and/or monitoring of disease, e.g., cancer. The methods provide ultra-high sensitivity and specificity, and include the use of microfluidic isolation of CTCs and digital detection of RNA derived from the CTCs.