The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Feb. 28, 2019
Applicants:

Roche Sequencing Solutions, Inc., Pleasanton, CA (US);

Kapa Biosystems, Inc., Wilmington, MA (US);

Inventors:

Aruna Arcot, Fremont, CA (US);

Daleen Badenhorst, Wellington, ZA;

Rui Chen, Fremont, CA (US);

Toummy Guettouche, Pleasanton, CA (US);

Ashley Hayes, San Francisco, CA (US);

Jenny A. Johnson, Castro Valley, CA (US);

Severine Margeridon, Castro Valley, CA (US);

Martin Ranik, Cape Town, ZA;

Persis Wadia, Fremont, CA (US);

Alexandra Hui Wang, Mountain View, CA (US);

Assignees:

Roche Sequencing Solutions, Inc., Pleasanton, CA (US);

KAPA Biosystems, Inc., Wilmington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); C12Q 1/6874 (2018.01); C12N 15/10 (2006.01); C12Q 1/6855 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12N 15/1068 (2013.01); C12Q 1/6855 (2013.01);
Abstract

The invention is a novel method of separately sequencing each strand of a nucleic acid involving the use of an adaptor comprising a strand cleavage site or a strand synthesis termination site. The adaptor may also be self-priming at the strand cleavage site.


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