The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Oct. 24, 2017
Applicant:
Chr. Hansen Hmo Gmbh, Rheinbreitbach, DE;
Inventors:
Assignee:
Chr Hansen HMO GmbH, Rheinbreitbach, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/18 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01); C12N 9/12 (2006.01); C12N 9/16 (2006.01); C12N 9/88 (2006.01); C12N 9/90 (2006.01); C12N 15/52 (2006.01); C12N 15/70 (2006.01); C07K 14/24 (2006.01);
U.S. Cl.
CPC ...
C12P 19/18 (2013.01); C07K 14/24 (2013.01); C12N 9/0006 (2013.01); C12N 9/1051 (2013.01); C12N 9/12 (2013.01); C12N 9/1205 (2013.01); C12N 9/1241 (2013.01); C12N 9/16 (2013.01); C12N 9/88 (2013.01); C12N 9/90 (2013.01); C12N 15/52 (2013.01); C12N 15/70 (2013.01); C12Y 101/01271 (2013.01); C12Y 204/01065 (2013.01); C12Y 207/01011 (2013.01); C12Y 207/07013 (2013.01); C12Y 401/02013 (2013.01); C12Y 402/01047 (2013.01); C12Y 504/02008 (2013.01);
Abstract
The present invention relates to a method for producing fucosylated oligosaccharides by using a recombinant prokaryotic host cell that is cultivated on a gluconeogenic substrate, as well as to the host cell and its use. The host cell is genetically modified in that the activity of a fructose-6-phosphate converting enzyme is abolished or lowered, and the transport of the produced fucosylated oligosaccharide through the cell membrane is facilitated by an exogenous transport protein.