The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Oct. 28, 2020
Applicant:

MD Healthcare Inc., Seoul, KR;

Inventor:

Yoon-Keun Kim, Paju-si, KR;

Assignee:

MD HEALTHCARE INC., Seoul, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/88 (2006.01); C12Q 1/06 (2006.01); C12Q 1/686 (2018.01); C12Q 1/6886 (2018.01); A61K 9/127 (2006.01); A61K 35/74 (2015.01); C12N 1/20 (2006.01); C12Q 1/689 (2018.01); C12R 1/01 (2006.01);
U.S. Cl.
CPC ...
C12N 15/88 (2013.01); A61K 9/1271 (2013.01); A61K 35/74 (2013.01); C12N 1/20 (2013.01); C12N 1/205 (2021.05); C12Q 1/06 (2013.01); C12Q 1/686 (2013.01); C12Q 1/689 (2013.01); C12Q 1/6886 (2013.01); C12R 2001/01 (2021.05);
Abstract

The present invention relates to vesicles derived from genusbacteria and a use thereof, the present inventors experimentally confirmed that the vesicles were significantly decreased in clinical samples derived from patients with a malignant disease such as gastric cancer, colorectal cancer, pancreatic cancer, bile duct cancer, breast cancer, ovarian cancer, bladder cancer, prostate cancer and lymphoma, a cardiovascular disease such as myocardial infarction, cardiomyopathy, atrial fibrillation, variant angina, and stroke, diabetes mellitus, and Parkinson's disease as compared to normal persons, and the vesicles suppressed the secretion of inflammatory mediators by pathogenic vesicles and suppressed the occurrence of cancer, so that the vesicles derived from genusbacteria may be usefully used for the purpose of developing a method for diagnosing a malignant disease such as gastric cancer, colorectal cancer, pancreatic cancer, bile duct cancer, breast cancer, ovarian cancer, bladder cancer, prostate cancer and lymphoma, a cardiovascular disease such as myocardial infarction, cardiomyopathy, atrial fibrillation, variant angina, and stroke, diabetes mellitus, and Parkinson's disease, and a composition for preventing or treating the diseases or an inflammatory disease.


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