The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Feb. 01, 2022
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Erik Funder, Hørsholm, DK;
Natascha Hruschka, Basel, CH;
Susanne Kammler, Hørsholm, DK;
Erich Koller, Basel, CH;
Brian Leonard, Basel, CH;
Souphalone Luangsay, Basel, CH;
Susanne Mohr, Basel, CH;
Tobias Nilsson, Basel, CH;
Søren Ottosen, Hørsholm, DK;
Lykke Pedersen, Hørsholm, DK;
Søren V. Rasmussen, Hørsholm, DK;
Steffen Schmidt, Hørsholm, DK;
Sabine Sewing, Basel, CH;
Daniel Turley, Basel, CH;
Johanna Marie Walther, Basel, CH;
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Abstract
The present disclosure provides antisense oligonucleotides targeting Regulator of telomere elongation helicase 1 (RTEL1). The disclosure also provides, enhanced antisense oligonucleotides targeting RTEL1 for use in treating and/or preventing a hepatitis B virus (HBV) infection. Also disclosed are pharmaceutical compositions and their use.