The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Dec. 04, 2020
Applicants:
Augusta University Research Institute, Inc., Augusta, GA (US);
Department of Veterans Affairs, Washington, DC (US);
Inventors:
Assignees:
Augusta University Research Institute, Inc., Augusta, GA (US);
Department of Veterans Affairs, Washington, DC (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/24 (2013.01); A61K 45/06 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2319/30 (2013.01);
Abstract
Antibodies and antigen binding fragments thereof that immunospecifically bind OPN (OPN) and inhibit OPN activity are provided herein. The disclosed antibodies and antigen binding fragments are useful for modulating signal transduction through OPN proteins. The antibodies and antigen-binding fragments are useful for the treatment or prevention of cancer, osteoporosis, or other immune diseases.