The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Nov. 02, 2018
Applicant:
Aveo Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Jeno Gyuris, Lincoln, MA (US);
Lorena Lerner, Newton Centre, MA (US);
Assignee:
AVEO Pharmaceuticals, Inc., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/22 (2006.01); C07K 14/475 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); C07K 14/475 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01);
Abstract
The invention provides methods and compositions for treating a subject having a renal-related disorder, such as chronic kidney disease (CKD), end stage renal failure, diabetes, insulin resistance, kidney hypertrophy, kidney hypotrophy, polycystic kidney disease, proteinuria, hyperglycemia, hyperuricemia, gout, kidney stones, hypertension or hypertensive nephropathy, dyslipidemia, anemia and/or reduced erythropoietin production, iron deficiency or hyperfiltration. The methods and compositions use or contain a composition that reduces or inhibits GDF15 activity.