The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Aug. 09, 2021
Applicant:

Adma Biologics, Inc., Ramsey, NJ (US);

Inventors:

James Mond, Silver Spring, MD (US);

Adam S. Grossman, Saddle River, NJ (US);

Assignee:

ADMA BIOMANUFACTURING, LLC, Boca Raton, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); C07K 16/06 (2006.01); A61K 9/00 (2006.01); A61K 35/16 (2015.01);
U.S. Cl.
CPC ...
C07K 16/1275 (2013.01); A61K 9/0019 (2013.01); A61K 35/16 (2013.01); C07K 16/06 (2013.01); C07K 16/065 (2013.01); C07K 2317/10 (2013.01); C07K 2317/21 (2013.01);
Abstract

The present invention relates to compositions and methods for the treatment of infection caused by. In particular, the invention provides human hyperimmune globulin and compositions thereof for preventing or treating pneumococcal infection. The invention provides methods of producing hyperimmune globulin containing high titers of opsonophagocytic anti-pneumococcal antibodies, compositions containing same, and methods of using the compositions for the prevention and treatment of pneumococcal infection. The invention further provides methods of preventing or treating pneumococcal infection (e.g., upper respiratory infections (e.g., bronchitis, otitis, sinusitis, etc.)) in immunocompromised subjects via administration of hyperimmune globulin compositions of the invention (e.g., containing a high titer of opsonophagocytic anti-pneumococcal antibodies) to immunocompromised subjects.


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