The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Feb. 22, 2021
Applicants:
LA Trobe University, Bundoora, AU;
The University of Queensland, St. Lucia, AU;
Inventors:
Begona Heras, Victoria, AU;
Jason Paxman, Victoria, AU;
Mark Schembri, Queensland, AU;
Alvin Lo, Victoria, AU;
Assignees:
La Trobe University, Bundoora, AU;
The University of Queensland, St. Lucia, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); A61P 31/04 (2006.01); A01N 63/50 (2020.01); A61K 39/40 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1232 (2013.01); A01N 63/50 (2020.01); A61K 39/40 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01);
Abstract
The present disclosure relates to compositions and methods for inhibiting bacterial aggregation, and in particular, to compositions and methods that inhibit autotransporter-mediated bacterial aggregation or attachment. Described herein are autotransporter binding molecules such as antibodies and antigen binding fragments thereof. The autotransporter binding molecules block self-association between autotransporters and autotransporter-mediated surface attachment.