The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Aug. 12, 2021
Applicant:
Kahr Medical Ltd., Jerusalem, IL;
Inventors:
Noam Shani, Zikhron-Yaakov, IL;
Yosi Gozlan, Rehovot, IL;
Michal Dranitzki Elhalel, Shoresh, IL;
Edwin Bremer, Groningen, NL;
Ido Kaminsky, Ramat-Gan, IL;
Assignee:
KAHR Medical Ltd., Modiln Makabim-ReUt, IL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01); C07K 14/705 (2006.01); A61P 35/00 (2006.01); A61K 38/17 (2006.01); A61K 47/65 (2017.01); A61P 35/02 (2006.01); C07K 16/28 (2006.01); C12N 5/0783 (2010.01); C12N 15/85 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70578 (2013.01); A61K 47/65 (2017.08); A61P 35/02 (2018.01); C07K 14/70596 (2013.01); C07K 16/2863 (2013.01); C07K 16/2887 (2013.01); C07K 16/2893 (2013.01); C12N 5/0638 (2013.01); C12N 15/85 (2013.01); A61K 38/00 (2013.01);
Abstract
SIRP1alpha-41BBL fusion proteins are provided. Accordingly, there is provided a SIRPalpha-41BBL fusion protein comprising a single amino acid linker between the SIRPalpha and the 41BBL. Also there is provided a SIRPalpha-41BBL fusion protein in a form of at least a homo-trimer. Also provided are polynucleotides and nucleic acid constructs encoding the SIRP1alpha-41BBL fusion protein, host-cells expressing the SIRP1alpha-41BBL fusion protein and methods of use thereof.