The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Aug. 09, 2022
University of Maryland, Baltimore, Baltimore, MD (US);
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Scott Thompson, Baltimore, MD (US);
Adam Van Dyke, Baltimore, MD (US);
Craig Thomas, Gaithersburg, MD (US);
Patrick Morris, Laurel, MD (US);
UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, Bethesda, MD (US);
Abstract
The present invention relates to novel alpha5 subunit-selective negative allosteric modulators of GABAreceptors that have been deuterated to improve their medicinal properties by prolonging their half-lives, rendering them useful as fast-acting pharmaceutical treatments for depression related disorders.