The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Oct. 07, 2022
Applicants:

Abbvie Inc., North Chicago, IL (US);

Genentech, Inc., South San Francisco, CA (US);

The Walter and Eliza Hall Institute of Medical Research, Parkville, AU;

Inventors:

Milan Bruncko, Green Oaks, IL (US);

Hong Ding, Gurnee, IL (US);

George A. Doherty, Libertyville, IL (US);

Steven W. Elmore, Northbrook, IL (US);

Lisa A. Hasvold, Grayslake, IL (US);

Laura Hexamer, Grayslake, IL (US);

Aaron R. Kunzer, Schaumburg, IL (US);

Xiaohong Song, Grayslake, IL (US);

Andrew J. Souers, Evanston, IL (US);

Gerard M. Sullivan, Lake Villa, IL (US);

Zhi-Fu Tao, Gurnee, IL (US);

Gary T. Wang, Libertyville, IL (US);

Le Wang, Vernon Hills, IL (US);

Xilu Wang, Grayslake, IL (US);

Michael D. Wendt, Vernon Hills, IL (US);

Robert Mantei, Franklin, WI (US);

Todd M. Hansen, Grayslake, IL (US);

Assignees:

AbbVie Inc., North Chicago, IL (US);

Genentech, Inc., South San Francisco, CA (US);

The Walter and Eliza Hall Institute of Medical Research, Parkville, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 519/00 (2006.01); C07D 471/04 (2006.01); C07D 209/82 (2006.01); C07D 403/12 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/496 (2013.01); C07D 209/82 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 471/04 (2013.01); C07D 519/00 (2013.01); Y02A 50/30 (2018.01);
Abstract

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.


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