The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Jun. 04, 2021
Applicant:

Receptos Llc, New York, NY (US);

Inventors:

Minhua Chen, Suzhou, CN;

Yanfeng Zhang, Suzhou, CN;

Xiaoting Zhai, Suzhou, CN;

Kaiqiang Yan, Suzhou, CN;

Chaohui Yang, Suzhou, CN;

Xiaoyu Zhang, Suzhou, CN;

Assignee:

RECEPTOS LLC, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 271/06 (2006.01); A61P 1/04 (2006.01); A61P 25/00 (2006.01); A61P 37/02 (2006.01); A61P 1/00 (2006.01); A61K 31/4245 (2006.01);
U.S. Cl.
CPC ...
C07D 271/06 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present disclosure relates to novel crystalline forms of ozanimod and preparation method thereof. The provided crystalline forms of ozanimod comprise crystalline form CS9, crystalline form CS10 and crystalline form CS11, and can be used for treating autoimmune diseases, particularly used for preparing drugs for treating multiple sclerosis and ulcerative colitis. The crystalline forms of the present disclosure have one or more advantages in solubility, stability, hygroscopicity and processability and provide new and better choices for the preparation of ozanimod drug product, and are very valuable for drug development.


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