The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Sep. 09, 2022
Applicant:

Reuter Chemische Apparatebau KG, Freiburg, DE;

Inventors:

Karl Reuter, Gundelfingen, DE;

Tobias Wedel, Karlsruhe, DE;

Viktor Meier, Gundelfingen, DE;

Mark Kantor, Freiburg, DE;

Vasyl Andrushko, Karlsruhe, DE;

Florian Stolz, Denzlingen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/56 (2006.01); C07D 211/60 (2006.01);
U.S. Cl.
CPC ...
C07D 211/56 (2013.01); C07D 211/60 (2013.01);
Abstract

The present invention relates to a process for the preparation of enantiomerically enriched 3-aminopiperidine, as in particular of its R-enantiomer (R)-3-aminopiperidine. The invention also relates to an enantiomerically enriched intermediate of said process and to specific acid-addition salts of 3-aminopiperidine (hereinafter also APIP) that are useful for obtaining a single enantiomer of APIP, and to crystalline (R)-3-aminopiperidine-dihydrochloride-monohydrate and crystalline (S)-3-aminopiperidine-dihydrochloride-monohydrate.


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