The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Mar. 28, 2018
Applicants:
The Broad Institute, Inc., Cambridge, MA (US);
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Jonathan Goldstein, Cambridge, MA (US);
Matthew Meyerson, Boston, MA (US);
Craig Strathdee, Cambridge, MA (US);
Assignees:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
The Broad Institute, Inc., Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); G01N 33/574 (2006.01); A61K 48/00 (2006.01); A61K 38/46 (2006.01); C12N 5/09 (2010.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0025 (2013.01); A61K 38/465 (2013.01); A61K 45/06 (2013.01); C12N 5/0693 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); G01N 33/57492 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01); G01N 2333/70567 (2013.01);
Abstract
The present disclosure provides compositions and methods for the treatment of PPARG activated cancer. For example, the present disclosure provides PPARG signaling modulators for the treatment of bladder cancer. In particular, therapeutic and/or prophylactic compositions and uses of PPARG inverse-agonists are described.