The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

May. 05, 2017
Applicants:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

The Wistar Institute of Anatomy and Biology, Philadelphia, PA (US);

Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA (US);

Inventors:

David B. Weiner, Merion, PA (US);

Kar Muthumani, Cherry Hill, NJ (US);

Niranjan Sardesai, Blue Bell, PA (US);

Assignees:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

The Wistar Institute of Anatomy and Biology, Philadelphia, PA (US);

Inovio Pharmaceuticals, Plymouth Meeting, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12N 15/85 (2006.01); C07K 16/28 (2006.01); A61K 31/7088 (2006.01); A61P 35/00 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001129 (2018.08); A61K 31/7088 (2013.01); A61K 39/395 (2013.01); A61P 35/00 (2018.01); C07K 16/2803 (2013.01); C07K 16/2818 (2013.01); C07K 16/2878 (2013.01); C12N 15/85 (2013.01); A61K 2039/505 (2013.01); A61K 2039/53 (2013.01);
Abstract

Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody or fragment thereof that targets an immune checkpoint molecule. The disclosure also provides a method of preventing and/or treating disease in a subject using said composition and method of generation.


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