The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Mar. 22, 2021
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Angela M. Belcher, Lexington, MA (US);
Uyanga Tsedev, Somerville, MA (US);
Fred Lam, Brookline, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/76 (2015.01); A61K 47/69 (2017.01); A61K 47/64 (2017.01); A61K 9/00 (2006.01); C12N 7/00 (2006.01); C12N 15/70 (2006.01); C12N 15/861 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/76 (2013.01); A61K 47/6901 (2017.08); C12N 7/00 (2013.01); C12N 15/70 (2013.01); C12N 15/861 (2013.01); A61K 9/0019 (2013.01); A61K 47/6415 (2017.08); A61K 49/0021 (2013.01); C12N 2795/14121 (2013.01); C12N 2795/14122 (2013.01); C12N 2795/14131 (2013.01); C12N 2795/14132 (2013.01); C12N 2800/202 (2013.01); C12N 2810/40 (2013.01);
Abstract
Provided are engineered phages populations, which are homogeneous in length, as well as methods of making and methods of using such phages. Also provided are engineered chlorotoxin-phages as well as their methods of making and using. The disclosed homogeneous phage populations and chlorotoxin-phages may be used, for example, for treating and/or imaging tumors, such as central nervous system tumors.