The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2024
Filed:
Nov. 08, 2019
Applicant:
Viacyte, Inc., San Diego, CA (US);
Inventors:
Laura Martinson, San Diego, CA (US);
Evert Kroon, San Diego, CA (US);
Kevin D'Amour, San Diego, CA (US);
Emmanuel Edward Baetge, Encinitas, CA (US);
Assignee:
ViaCyte, Inc., San Diego, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/39 (2015.01); C12N 5/071 (2010.01); A61K 38/26 (2006.01); A61K 38/28 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/39 (2013.01); A61K 38/26 (2013.01); A61K 38/28 (2013.01); C12N 5/0676 (2013.01); C12N 5/0678 (2013.01); A61K 35/12 (2013.01); C12N 2500/38 (2013.01); C12N 2501/10 (2013.01); C12N 2501/105 (2013.01); C12N 2501/113 (2013.01); C12N 2501/115 (2013.01); C12N 2501/119 (2013.01); C12N 2501/12 (2013.01); C12N 2501/16 (2013.01); C12N 2501/33 (2013.01); C12N 2501/385 (2013.01); C12N 2501/41 (2013.01); C12N 2501/415 (2013.01); C12N 2501/42 (2013.01); C12N 2501/58 (2013.01); C12N 2501/999 (2013.01); C12N 2506/02 (2013.01);
Abstract
Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy.