The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2024

Filed:

Jan. 08, 2019
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventor:

Guobao Wang, Sacramento, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 6/00 (2006.01); G16H 50/50 (2018.01); G16H 30/40 (2018.01); A61B 6/03 (2006.01); A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61B 6/5217 (2013.01); A61B 6/037 (2013.01); A61B 6/507 (2013.01); A61K 51/04 (2013.01); A61K 51/0455 (2013.01); A61K 51/0482 (2013.01); A61K 51/0491 (2013.01); G16H 30/40 (2018.01); G16H 50/50 (2018.01);
Abstract

Systems and methods are disclosed for quantifying blood flow using time-varying kinetic modeling of high temporal-resolution dynamic positron emission tomography (PET) data. A single tracer is introduced into the body. A first set of images is acquired, via PET, of at least a portion of the body at a plurality of predetermined time intervals. Based on the first set of images, an intensity of the tracer in the at least the portion of the body is determined as a function of time. The intensity of the tracer as a function of time is modeled using a time-varying kinetic model. Based on the model, the blood flow through the at least the portion of the body is quantified. Additional images may be acquired and used to quantify additional parameter(s), such as glucose metabolism, amyloid load, etc., with the single tracer.


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